E-ISSN 3043-6125 | ISSN 3043-6133
 

Research Article 


Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis

Friday Attah, Moses E Abalaka.


Abstract
Plants have served as a traditional remedy for humans throughout history, due to their availability, perceived safety, and easy access. Mitracarpus scaber, a herb historically appreciated for its usefulness in treating various skin problems, was the focus of this current research aiming to identify the plant's phytocompounds content using Fourier-transform infrared spectroscopy (FTIR) and gas chromatography-mass spectrometry (GC-MS) methods. The presence of phenols, saponins, flavonoids, steroids, alkaloids, tannins, and terpenoids were identified through phytochemical screening. The plant's chemical composition was analysed by FTIR, the results indicate the presence of the following functional groups: C=C, C-Cl, C-N, S=O, C-N, O-H, N-O, C=O, C-H, and N-H. The GC-MS result revealed 18 phytocompounds, with the following being the most abundant: Oleic acid (23.22%), n-Hexadecanoic acid (14.60%), 1, 3-dioxolane (13.50%), 11-Octadecenoic acid, methyl ester (10.12%), Hexadecanoic acid, methyl ester (9.18%), 4-Trifluoroacetoxy hexadecane (5.97%), Octadecanoic acid, methyl ester (4.58%), and Stearic acid methyl ester (3.08%), all of which have medicinal value. The study revealed Mitracarpus scaber's medicinal potential, emphasizing its importance in pharmaceutical research and the development of novel drugs, particularly for skin infections. More pharmacological research is needed to fully explore the therapeutic effects of these bioactive substances on skin disease causative agents.

Key words: GC-MS, FTIR, Phytoconstituent, Phytochemical and Plant


 
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Pubmed Style

Attah F, Abalaka ME. Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. CUJOSTECH. 2024; 1(2): 21-26. doi:10.5455/CUJOSTECH.241001


Web Style

Attah F, Abalaka ME. Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. https://www.cujostech.com.ng/?mno=196050 [Access: February 24, 2025]. doi:10.5455/CUJOSTECH.241001


AMA (American Medical Association) Style

Attah F, Abalaka ME. Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. CUJOSTECH. 2024; 1(2): 21-26. doi:10.5455/CUJOSTECH.241001



Vancouver/ICMJE Style

Attah F, Abalaka ME. Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. CUJOSTECH. (2024), [cited February 24, 2025]; 1(2): 21-26. doi:10.5455/CUJOSTECH.241001



Harvard Style

Attah, F. & Abalaka, . M. E. (2024) Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. CUJOSTECH, 1 (2), 21-26. doi:10.5455/CUJOSTECH.241001



Turabian Style

Attah, Friday, and Moses E Abalaka. 2024. Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. Confluence University Journal of Science and Technology, 1 (2), 21-26. doi:10.5455/CUJOSTECH.241001



Chicago Style

Attah, Friday, and Moses E Abalaka. "Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis." Confluence University Journal of Science and Technology 1 (2024), 21-26. doi:10.5455/CUJOSTECH.241001



MLA (The Modern Language Association) Style

Attah, Friday, and Moses E Abalaka. "Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis." Confluence University Journal of Science and Technology 1.2 (2024), 21-26. Print. doi:10.5455/CUJOSTECH.241001



APA (American Psychological Association) Style

Attah, F. & Abalaka, . M. E. (2024) Phytochemical screening and Identification of Bioactive compounds of Methanol extracts of Mitracarpus scaber through FTIR and GCMS Analysis. Confluence University Journal of Science and Technology, 1 (2), 21-26. doi:10.5455/CUJOSTECH.241001